The Interaction of AFB1 Aflatoxin and Lactococcin A; Molecular Docking

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dc.authoridhttps://orcid.org/0000-0003-2104-6019
dc.authoridhttps://orcid.org/0000-0001-5772-2838
dc.authoridhttps://orcid.org/0000-0002-5151-4576
dc.contributor.authorÖzgen, Arzu
dc.contributor.authorÜnlü, Nihan
dc.contributor.authorAksu Canbay, Canan
dc.date.accessioned2025-06-26T07:11:11Z
dc.date.available2025-06-26T07:11:11Z
dc.date.issued2024
dc.departmentSağlık Hizmetleri Meslek Yüksekokulu
dc.description.abstractAflatoxins (AF), which cause diseases in humans and animals, are mycotoxins produced by certain types of fungi. Bacteriocins are natural antimicrobial substances synthesized by bacteria. These substances that are in protein structure, generally have short chain and small molecular weight. According to the classification made by Klaenhammer, especially considering Gram (+) bacteria, bacteriocins are divided into 4 different classes. These are Class I (Class IA, Class IB), Class II (Class IIA, Class IIB, Class IIC, Class IID), Class III and Class IV. Enterocin A, Sakacin A, Lactococcin A can be given as examples of Class II bacteriocins. In this study, we examined the interaction of AFB1 aflatoxin (ligand) and Lactococcin A (protein) bacteriocin, which is in Class II, using Molecular Docking. The results showed that Lactococcin A molecule have the potential to be used for aflatoxin degradation.
dc.identifier.citationÖZGEN, A., ÜNLÜ, N., CANBAY, C. A. (2024). The Interaction of AFB1 Aflatoxin and Lactococcin A; Molecular Docking. Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 28(6),1352-1359. doi.org/10.16984/saufenbilder.1225098
dc.identifier.doihttps://doi.org/10.16984/saufenbilder.1225098
dc.identifier.endpage1359
dc.identifier.issn2147-835X
dc.identifier.issue6
dc.identifier.startpage1352
dc.identifier.urihttps://hdl.handle.net/11363/10004
dc.identifier.volume26
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorÖzgen, Arzu
dc.institutionauthorÜnlü, Nihan
dc.institutionauthoridhttps://orcid.org/0000-0003-2104-6019
dc.institutionauthoridhttps://orcid.org/0000-0001-5772-2838
dc.language.isoen
dc.publisherSakarya University
dc.relation.ispartofSakarya University Journal of Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAflatoxins (AF)
dc.subjectBacteriocins
dc.subjectMolecular docking
dc.subjectLactococcin A
dc.titleThe Interaction of AFB1 Aflatoxin and Lactococcin A; Molecular Docking
dc.typeArticle

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