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  Investigation of Toxic Pathological Findings in European Seabass (Dicentrarchus labrax (Linnaeus, 1758)) Applied with High-dose Chlorine Dioxide

  (Selcuk Universitesi, Veteriner Fakultesi, 2026) Vural, Eda; Çiftçi, Mustafa Kemal

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  dependent histopathological alterations were observed at higher exposure levels. these concentrations did not induce significant oxidative stress or apoptosis, although doseand 1.125 mg/L for short-term applications. Under the experimental conditions of this study, disinfectant in marine aquaculture for European seabass at concentrations between 0.750 rather than activation of these pathways. In conclusion, Chlorine dioxide may be used as a those of the control group, indicating a suppression or reduction relative to baseline levels Chlorine dioxide exposure. In several cases, biomarker levels were significantly lower than no significant induction of oxidative stress or apoptotic responses in liver tissue following Fas (pmol/L), Malondialdehyde (pmol/L), and P53/Tumour Protein P53 (pmol/L) showed (Caspase-3 (pmol/L), Tumour Necrosis Factor-α (pmol/L), Cytochrome-C (pmol/L), Apo-1/ dose (p < 0.001, n = 10 per group). ELISA analyses of oxidative stress and apoptosis biomarkers 0.75, and 1.125 mg/L), demonstrating a significant increase in tissue damage with increasing 2.25 mg/L) had significantly higher lesion scores compared with the low-dose groups (0.375, severity. Scoring results for gill and liver tissues indicated that high-dose groups (1.5, 1.875, and were scored as 0 in the control group, and scores from 1 to 4 were assigned based on lesion vacuolization, and necrosis in the liver; and oedema in the brain. Histopathological changes including degeneration, necrosis, and epithelial sloughing in the gills; hepatocyte swelling, gills and liver. Histopathological examinations revealed dose-related pathological alterations, biomarkers were evaluated in liver tissue. Macroscopically, haemorrhages were observed in the daily renewal of the disinfectant solution. In addition, oxidative stress and apoptosis-related seabass. Fish were exposed to Chlorine dioxide for 7 days under semi-static conditions, with and organs (skin, gills, liver, heart, kidneys, and intestines) of 9–19-month-old European at different concentrations (0.375, 0.750, 1.125, 1.5, 1.875, and 2.25 mg/L) in various tissues this value, the present study aimed to evaluate the pathological effects of Chlorine dioxide dioxide for European seabass was determined experimentally to be 1.33 mg/L. Based on effects in fish.Before the experiment, the 96-h median lethal concentration (LC₅₀) of Chlorine strategies. Nevertheless, these agents may be ineffective and can cause undesirable pathological disinfectants, such as ozone and chlorine, are also commonly used as essential complementary systems and ultraviolet (UV) treatment, are commonly used to maintain water quality; chemical parameters affecting fish health and farm productivity. Physical approaches, such as filtration labrax) aquaculture. Among these factors, water quality management is one of the most critical major constraints that can significantly limit production in European seabass (Dicentrarchus cultured in coastal farming systems. However, diseases and environmental stressors remain labrax) accounts for approximately 37% of marine aquaculture production and is widely global food security and national economies. In Türkiye, the European seabass (Dicentrarchus Aquatic species are important sources of high-quality protein and contribute significantly to

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  A Privacy-Preserving Consumer-Centric IoMT Framework Using TEE-Enabled Federated Learning, CP-ABE, and Blockchain

  (Institute of Electrical and Electronics Engineers Inc., 2026) Ahmed, Farooq; Zhou, Teng; Mahmood, Jabar; Alzahrani, Bander A.; Chaudhry, Shehzad Ashraf

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  The rapid expansion of the Internet of Medical Things (IoMT) has transformed healthcare delivery by enabling real-time monitoring, advanced diagnostics, and efficient data sharing. However, current systems in large-scale, decentralized environments face significant challenges in privacy, security, trust, and interoperability. This paper presents a Federated Learning framework for a consumer-centric IoMT system that provides secure, resilient data exchange against AI-enabled attacks through privacy-preserving learning, decentralized authentication, and hardware-based trust. It integrates trusted execution environments (TEEs), blockchain-based trust management, and ciphertext-policy attribute-based encryption (CP-ABE) to enable secure collaboration without exposing raw data. We provide a security proof in the Real-or-Random (RoR) model and conduct a comprehensive performance analysis covering computation, communication, storage, smart contract processing, and throughput. Experimental results show a 40% reduction in authentication latency, a 27% decrease in computational overhead, a 98% drop in energy use, and a 35% increase in throughput compared to existing schemes. These findings demonstrate that the proposed framework offers high scalability robust security, and privacy protection, making it ideal for the next-generation healthcare ecosystem.

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  Do Digitalization and Technological Innovation Foster the Achievement of the Sustainable Development Goals? Evidence from EU’s Newer Member States

  (Emerald Publishing, 2026) Yazıcı, Ayşe Meriç; Öztırak, Mesut; Bayram, Vildan

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  Purpose – This study aims to evaluate the impact of digitalization and technological innovation on the achievement of Sustainable Development Goals (SDGs) in 11 EU member states that joined after 2004. The research specifically investigates how the influence of these factors varies across different levels of sustainability performance in the post-accession period. Design/methodology/approach – Using annual data from 2000 to 2023, the study applies the quantile regression method to capture heterogeneous effects across countries with differing SDG performance levels. This approach allows for an in-depth analysis of whether and how digitalization and innovation affect sustainability outcomes at lower, median and higher levels of development. Findings – The results reveal that digitalization has a consistently positive and statistically significant impact on SDG performance across all quantiles, with stronger effects observed in countries with lower sustainability scores. In contrast, technological innovation shows a more limited and diminishing effect at higher quantiles, suggesting that innovation alone is not sufficient without complementary policy or institutional support. The study confirms the crucial role of digital transformation in accelerating sustainable development in emerging EU economies. Originality/value – This study provides novel insights into the differentiated role of digitalization and innovation in promoting sustainability across various stages of development. Unlike previous research that primarily focused on advanced economies, this paper emphasizes the importance of tailored digital investment strategies in newer EU member states, offering practical implications for policymakers seeking to close the SDG performance gap within the European Union.

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  The Association between Synthetic Oxytocin Administration During Labor and Birth Interventions, Maternal Anxiety, and Newborn Stress Levels: A Comparative Study

  (İstanbul Gelişim Üniversitesi Yayınları / Istanbul Gelisim University Press, 2026) Öztaş, Hatice Gül; Sabancı Baransel, Esra; Keçeli, Melek Nur

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  Aim: The objective of this study was to examine the associations between synthetic oxytocin administration during labor, birth intervention rates, maternal anxiety levels, and newborn stress levels. Method: This cross-sectional analytical study included 300 postpartum women divided into two groups: those who received synthetic oxytocin (n=197) and those who did not (n=103). Data were collected using the Personal Information Form, Labor Observation Form, State Anxiety Inventory (SAI), and Newborn Stress Scale (NSS). Multivariable regression analyses were performed to assess the independent associations while adjusting for potential obstetric and sociodemographic confounders. Results: In unadjusted analyses, fundal pressure, placental retention, and episiotomy rates were higher in the synthetic oxytocin group (p< 0.05). Women in this group also had higher SAI scores (51.43±3.39 vs. 50.11±3.54, p=0.040). and higher newborn stress levels (p=0.002). After adjusting for potential confounders in multivariable logistic regression, synthetic oxytocin administration remained significantly associated with increased odds of episiotomy (OR=2.04, 95% CI: 1.02–4.00, p=0.042) and placental retention (OR=7.14, 95% CI: 1.49–33.33, p=0.014). However, multivariable linear regression models for maternal anxiety (p=0.077) and newborn stress (p=0.052) did not reach overall statistical significance, indicating that these specific factors should not be interpreted as independently associated with oxytocin administration. Conclusion: The findings suggest that synthetic oxytocin administration is associated with higher rates of specific obstetric interventions such as episiotomy and placental retention. Due to overall model limitations, the independent relationships regarding maternal anxiety and neonatal stress should be interpreted with caution. Healthcare professionals should prioritize individualized, evidence-based labor management to minimize unnecessary medical interventions.

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  Rheology of Melting and Heat Transfer Progress of Gallium in Heterogeneous Chamber Containing Metal Foam and Nanoparticles Under Influence of Magnetic Field

  (Springer Science and Business Media Deutschland GmbH, 2026) Chibani, Atef; Merouani, Slimane; Badji, Riad; Rashid, Farhan Lafta; Eid, Mohamed R.; Souayeh, Basma; Mahariq, Ibrahim; Kezzar, Mohamed; Sari, Mohamed Rafik

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  In this work, melting characteristics and heat transfer enhancement of gallium as phase change material (PCM) surrounded by heterogeneous chamber filled with metal foam and Al2O3 nanoparticles under magnetic field are investigated. The main challenge rather is the low thermal conductivity of PCMs which in turn limits the performance of PCM based TESSs. Numerical simulations were performed using a 2D transient model developed by employing the enthalpy-porosity model and Darcy–Brinkman equations for the porous domain; where one of the boundary walls was kept at a heated temperature of 43 °C. It is found that the incorporation of metallic foam and nanoparticles greatly enhances both thermal conductivity and facilitates uniform melt. In addition, the magnetic field promotes such convective heat transfer, speeds up the melting rate, and raises the mean Nusselt number and surface heat flux. These results indicate that the integration of metal foams and nano/micro particles, and magnetic fields could be used to maximize the thermal performance of PCMs, which can lead to advanced TES applications with a high potential.

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