İstanbul Gelişim Üniversitesi Kurumsal Açık Erişim Arşivi
DSpace@Gelişim, İstanbul Gelişim Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve yayınların etkisini artırmak için telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Öğe Türü: Öğe , Biosynthesis of Zinc Oxide Nanoparticles Using Dried Leaves of Camellia sinensis: Methods to Characterize and Assess Their Effects on Mesenchymal Stem Cell Viability(Humana Press, 2025) Yeşilkır Baydar, Serap; Akgül Çağlar, Tuba; Koç, Fatma EbruStem cell nanotechnology (SCN) is an important scientific field to guide stem cell-based research of nanoparticles. Currently, nanoparticles (NPs) have a rich spectrum regarding the sources from which they are obtained (metallic, polymeric, etc.), the methods of obtaining them (physical, chemical, biological), and their shape, size, electrical charge, etc. properties. It is also essential to expand green synthesis applications for the use of NPs in the field of biomedical sciences. For this purpose, there is a need to produce NPs using biological sources (plant, microorganism, algae, yeast etc.…), characterization and investigation of their effects on biological activities of stem cells. This process involves long and laborious procedures, and there may be differences in methods between individual laboratories.In this protocol, biofabrication and characterization of ZnO NPs using dried leaves of Camellia sinensis is described. This experimental setup includes conventional and novel methods that can be applied to biofabricate and characterize the NPs and to examine the viability, apoptotic, and necrotic effects on human adipose tissue-derived mesenchymal stem cells (ADMSCs) in vitro.Öğe Türü: Öğe , Analysis of the relationship between physical education majors' perceptions of their body shape and fatphobia(Frontiers Research Foundation, 2026) Sayın Temur, Canan; Koç, Mustafa Can; Iconomescu, Teodora Mihaela; Talaghir, Laurentiu-GabrielPurpose: The purpose of this study is to investigate whether body shape perceptions and fat phobia differ according to the gender and year of study of PE teacher candidates. In addition, the study aims to investigate the possible relationship between actual and ideal body shape perceptions and fatphobia. Methods: The study involved a total of 141 PE teacher candidates. The participants’ mean age was 21.45 (±1.93) years (M female = 21.08 ± 1.56, M male = 21.73 ± 2.14). Data was collected using a Demo-graphic Information Form, a Fatphobia Scale, and a Figure Rating Scale. The Mann–Whitney U test, the Kruskal–Wallis test and the Spearman’s correlation analysis were used to analyze the data. Results: The results showed that there was no statistically significant difference between female and male teacher candidates’ levels of fatphobia. In contrast, there was a significant difference between their perceptions of current and ideal body shape. The results also showed that there was no difference between the perceived levels of fatphobia and the perceived current and ideal body shapes of the Grade Level 1st, 2nd, 3rd, and 4th-year PE teacher candidates. The findings revealed a lack of a statistically significant relationship between fatphobia and current body image and between fatphobia and ideal body image. Conclusion: As a result of the research, the fact that PE teacher candidates are moderately fatphobic, perceive themselves to be overweight, and idealize thinness to a higher degree than men has provided critical insights for educational policymakers.Öğe Türü: Öğe , Correction: From knowledge to action: how nutrition knowledge shapes sustainable eating and Mediterranean diet adherence(Frontiers Media S. A., 2026) Öngün Yılmaz, Hande; Arslan, Sedat; Tari Selçuk, Kevser; Bayram, Hatice Merve; Öztürkcan, ArdaThe author, Sedat Arslan, was erroneously assigned to “Department of Nutrition and Dietetics, Faculty of Health Sciences, Bandırma Onyedi Eylül University, Balıkesir, Türkiye.” Their correct affiliation is Affiliation 2, “Department of Nutrition and Dietetics, Faculty of Health Sciences, Bursa Uludag University, Bursa, Türkiye.” The authors, Hatice Merve Bayram and Arda Ozturkcan, were erroneously assigned to “Department of Nutrition and Dietetics, Faculty of Health Sciences, Bandirma Onyedi Eylül University, Balikesir, Türkiye.” They should be assigned to affiliation 3, “Department of Nutrition and Dietetics, Faculty of Health Sciences, Istanbul Gelisim University, Istanbul, Türkiye.” The original version of this article has been updated.Öğe Türü: Öğe , Ignored by the boss: a moderated-mediation study of boss phubbing(Frontiers Research Foundation, 2026) Balkaş, Jale; Taş, Mehmet; Günsel, Ayşe; Bozkurt, Serdar; Konakay, Gönül; Aksu, Bumin ÇağatayIntroduction: This study investigates the workplace implications of boss phubbing (BP)—a managerial behavior in which supervisors prioritize smartphone use over face-to-face interactions with employees. Drawing on Expectancy Violation Theory (EVT), Social Exchange Theory (SET), and Leader– Member Exchange (LMX), BP is conceptualized as a negative relational signal that can undermine employees’ job attitudes. Methods: A moderated mediation model was tested to examine whether satisfaction with supervision (JDI) mediates the relationship between BP and job satisfaction, and whether power distance moderates the direct and indirect effects. Survey data were collected from 412 full-time employees and analyzed using PROCESS Model 7 with bootstrapping. Results and discussion: BP significantly reduced satisfaction with supervision (JDI), which in turn fully mediated its effect on job satisfaction; the direct effect of BP on job satisfaction was not significant. Power distance did not moderate the direct path from BP to satisfaction with supervision (JDI) but did moderate the indirect effect, which was stronger for employees low in power distance. Together, these findings indicate that boss phubbing operates primarily through relational exchange processes and that cultural value orientations shape the extent to which inattentive leadership undermines employees’ job attitudes. These results contribute to the growing literature on digital workplace behaviors by clarifying how, and under what conditions, boss phubbing erodes employee outcomes.Öğe Türü: Öğe , Fasted-State Aerobic Exercise Enhances Cognition and Hippocampal BDNF Signaling in an Alzheimer’s Disease Rat Model(Plenum Press, 2025) Kırkbir, Fatih; Atasoy, Taner; Khodadadai, Davar; Sajedi, Heidar; Keskin, Özlem; Babaie, MohammadAlzheimer’s disease (AD) is a multifactorial disorder that demands a comprehensive management strategy. Both aerobic exercise training and intermittent fasting (IF) have been shown to ameliorate AD symptoms, yet the impact of exercise in the fasted state remains understudied. This study compared the effects of four weeks of moderate intensity treadmill running in either a fasted or a normal fed state on cognitive function and hippocampal BDNF signaling in an amyloid-β (Aβ)1–42-injected rat model of AD. Twenty month old male Wistar rats were allocated into five groups (n=12 each): AD, AD plus IF (ADIF), AD plus exercise training (ADET), AD plus IF plus exercise training (ADIFET), and control. AD was induced by bilateral intra hippocampal Aβ1–42 injection. Exercise interventions (fasted or fed) were conducted 5 days/week for 4 weeks. Aβ injection significantly impaired learning and memory and reduced hippocampal levels of PKA, CREB, and BDNF (p< 0.001). Both fasting and exercise independently elevated plasma and hippocampal β-hydroxybutyrate (βHB) (p< 0.001), with the highest βHB increase observed in the fasted-exercise group (p< 0.01). All intervention groups (ADIF, ADET, and ADIFET) demonstrated significant improvements in cognitive performance and hippocampal levels of PKA, CREB, and BDNF (p< 0.001). The combined fasting plus exercise group produced greater benefits than either IF or exercise alone (p< 0.05), and exercise alone outperformed fasting alone (p< 0.05). These findings indicate that aerobic exercise in the fasted state offers superior neuroprotective and cognitive benefits, likely via upregulation of βHB/PKA/ CREB/BDNF signaling, highlighting fasted state exercise as a promising therapeutic approach for AD.
