DSpace Arşivi :: Ana Sayfa

İstanbul Gelişim Üniversitesi Kurumsal Açık Erişim Arşivi

DSpace@Gelişim, İstanbul Gelişim Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve yayınların etkisini artırmak için telif haklarına uygun olarak Açık Erişime sunar.

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Effects of Minor Al, Ag, and Sb Additions on the Thermal, Microstructure and Microhardness of Zn–Sn–Cu–Bi High-Temperature Solder Alloys
(Pleiades Publishing, 2024) Aksöz, Sezen; Esener, Pınar Ata; Öztürk, Esra; Maraşlı, Necmettin
In the present study, the changes in microstructure, thermal conductivity (K), melting properties and microhardness (HV) adding of 0.05 wt % Al, Ag and Sb into Zn–5Sn–2Cu–1.5Bi (ZSCB) high temperature solder alloy were investigated. The addition of trace amounts of Al, Ag and Sb caused a significant improvement in K and HV values. Addition of 0.05 wt % of Al and Ag into the ZSCB alloy increased the K and HV values by 62% and in the range of 19–21%, respectively. The addition of 0.05 wt % of Sb increased the K and HV values by 32 and 36%, respectively.
Metabolite Profiling of Lavender (Lavandula pedunculata subsp. cariensis) Essential Oil and Investigation of Its Potential Antioxidant and Enzyme-Inhibitory Effects
(MDPI AG, 2026) Karageçili, Hasan; Özden, Eda Mehtap; Mutlu, Muzaffer; Bingöl, Zeynebe; Akıncıoğlu, Hülya; Köksal, Ekrem; Ceyhan Gören, Ahmet; Gülçin, İlhami
Background/Objectives:Lavandula cariensis species is cultivated uncommonly in the western region of Turkey. The colloquial appellations avayianos, karabasi, and myra are used to refer to the L. cariensis plant. The essential oil of L. cariensis was studied for its potential antiglaucoma, antioxidant, antidiabetic, and acetylcholinesterase inhibitory effects. Methods: The inhibitory effect of the essential oil of L. cariensis on the acetylcholinesterase (AChE), carbonic anhydrase II (CA II), and α-amylase enzymes was determined. Therefore, chemical profiles of L. cariensis' essential oil were identified using Gas Chromatography Mass Spectrometry (GC-MS) and as Chromatography with Flame Ionization Detection (GC-FID) analyses. Results: Camphor (39.73%), fenchone (19.49%), exobornyl acetate (6.81%), camphene (5.49%), and eucalyptol (5.49%) were the most abundant compounds in L. cariensis essential oil. Radical scavenging effect of the essential oil of L. cariensis was examined using 1,1-diphenyl-2-picrylhydrazyl (DPPH) (IC50: 231.0 ± 0.094 μg/mL) and 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) (IC50: 7.45 ± 0.013 μg/mL) radicals. Also, the ferric ions (Fe3+), cupric ions (Cu2+), and Fe3+-2,4,6-tri(2-pyridyl)-S-triazine (TPTZ) complex reducing capabilities were studied. Additionally, essential oil of L. cariensis indicated a comparable level of inhibition towards hCA II (IC50: 276.42 μg/mL), AChE (IC50: 14.22 μg/mL), and α-amylase (IC50: 475.63 μg/mL) enzymes. Conclusions: The evaluation of the antioxidant capabilities and enzyme inhibition profiling of the essential oil of L. cariensis will be made possible by this comprehensive study, which serves as a springboard for further research. The essential oil of L. cariensis demonstrated enzyme-inhibitory activities against target enzymes associated with Alzheimer's disease, diabetes, and glaucoma. Also, this study's in vitro inhibition suggests promising prospects.
Does piezocision induce root resorption or periodontal problems in class II patients?: A 2‑year follow‑up study
(Medknow Publications and Media Pvt. Ltd., 2026) Aksakallı, Sertaç; Ezirganlı, Şeref; Demir, Erhan
OBJECTIVE: This study aimed to evaluate the potential for root resorption and periodontal complications in patients with Class II malocclusion undergoing piezocision assisted orthodontic treatment over a 2 year follow up period. MATERIALS AND METHODS: Twenty patients (11 females, 9 males; mean age: 16.1 ± 2.8 years) requiring bilateral canine distalization and maxillary first premolar extraction were included in this split mouth study. One quadrant was randomly assigned to undergo piezocision, while the contralateral quadrant served as the control. Panoramic radiographs were utilized to assess root resorption at baseline (T1), and 2 years post treatment (T2). Additionally, gingival health and tooth mobility scores were evaluated. Statistical analyses were performed using the Wilcoxon signed rank test. RESULTS: No clinically significant root resorption was observed in either group. Mild resorption was noted on the upper canine of one patient in the piezocision group, while another patient in the control group exhibited resorption on the upper lateral incisor. Gingival health, and mobility scores decreased from T1 to T2 in both groups, with no statistically significant differences found between the piezocision and control sides. Scar formation on the attached gingiva was observed in one patient following piezocision; however, this was not associated with bone loss or increased periodontal pocket depth. CONCLUSION: Piezocision assisted orthodontic treatment did not result in clinically significant root resorption or adverse periodontal outcomes in patients with Class II malocclusion over a 2 year period. These findings support the safety of piezocision as a method for accelerating tooth movement without compromising periodontal health. Further research with larger sample sizes and histological assessments is recommended to validate these results.
Clinicopathologic Predictors and Nodal Burden Pattern of Skip Metastasis in Papillary Thyroid Carcinoma: A Multicenter Study
(J. Wiley, 2026) Yurdacan Şahin, Müge; Dural, Ahmet C.; Aydın, Hüsnü; Matlım Özel, Tuğba; Akbulut, Sezer; Çelik, Aykut; Yıldız, Görkem; Onuktav, Firdevs M.; Karatay, Hüseyin; Aylaz, Gökçe; Güzey, Deniz; Şahbaz, Nuri Alper; Canöz, Özden; Sürek, Ahmet; Çikot, Murat; Sarı, Serkan
Background: Skip metastasis (SM), defined as lateral lymph node metastasis without central involvement, is an important but unpredictable spread pattern in papillary thyroid carcinoma (PTC). This study aimed to determine its prevalence, identify clinicopathologic predictors, and develop a preoperative risk model. Methods: We retrospectively analyzed 130 PTC patients with histologically confirmed lateral metastasis who underwent total thyroidectomy, bilateral central neck dissection, and unilateral or bilateral lateral dissection at three tertiary centers between 2019 and 2025. Clinicopathologic and nodal variables were compared between the SM and non-skip metastasis (NSM) groups. Independent predictors were evaluated using multivariable logistic regression, and model performance was assessed with ROC AUC. Results: SM occurred in 12.3% of patients. SM was associated with older age, upper-pole tumor location, solitary intrathyroidal focus, and lower nodal burden. Independent predictors were age ≥ 39.5 years and upper-pole location, while same-lobe multifocality was inversely associated. The model showed good discrimination with an AUC of 0.841. Conclusion: Older patients with solitary upper-pole PTC warrant meticulous preoperative lateral-neck assessment. A simplified preoperative model incorporating age, tumor topography, and multifocality may support risk-based surgical planning.
The relationship among university students' recreational flow experience, psychological resilience, social connectedness, and life satisfaction
(Frontiers Research Foundation, 2026) Güllü, Sevim; Şahinler, Yunus; Genç, Ayça; Bozyiğit, Elif; Biçer Baikoğlu, Selin; Genç, Neşe; Akkoç, Orkun
Introduction: This study aimed to examine the relationships among recreational flow experience, social connectedness, psychological resilience, and life satisfaction in university students. Methods: The sample consisted of 810 (416 female, 394 male) university students from various universities in Istanbul who voluntarily participated in the study. Data were collected using four standardized measurement instruments: the Recreational Flow Experience Scale, the Social Connectedness Scale, the Brief Resilience Scale, and the Satisfaction with Life Scale. Statistical analyses were conducted using SPSS and Hayes' PROCESS Macro (Model 4) to test both direct and indirect association among the variables. Results: Recreational flow significantly is positively associated with social connectedness and psychological resilience. Social connectedness and psychological resilience each is positively associated with life satisfaction. Furthermore, the relationship between recreational flow and life satisfaction was accounted for by a parallel mediation structure, in which social connectedness and psychological resilience operated as complementary pathways. Discussion: These results indicate that both social and psychological processes contribute to explaining how recreational flow relates to life satisfaction. The study highlights the distinct roles of social connectedness and psychological resilience in strengthening the positive outcomes of recreational flow and provides empirical evidence on the interconnections among these four constructs in the university student population.