Levels of nitric oxide, asymmetric dimethyl arginine, symmetric dimethyl arginine, and L-arginine in patients with obsessive-compulsive disorder

Basit Öğe Kaydı
dc.authoridhttps://orcid.org/0000-0002-7303-0396en_US
dc.contributor.authorYılmaz, Enver Demirel
dc.contributor.authorÜstündağ, Mehmet Fatih
dc.contributor.authorGençer, Ali Görkem
dc.contributor.authorKıvrak, Yüksel
dc.contributor.authorÜnal, Özge
dc.contributor.authorBilici, Mustafa
dc.date.accessioned2023-10-03T16:15:24Z
dc.date.available2023-10-03T16:15:24Z
dc.date.issued2016en_US
dc.departmentİktisadi İdari ve Sosyal Bilimler Fakültesien_US
dc.description.abstractBackground/aim: We aimed to investigate and compare to healthy controls the variations in the levels of nitric oxide (NO), asymmetric dimethyl arginine (ADMA), symmetric dimethyl arginine (SDMA), and L-arginine levels in patients with obsessive-compulsive disorder (OCD). Materials and methods: We enrolled 30 patients with OCD and 30 healthy controls in the study consecutively. Diagnostic interviews of all participants were conducted with the Structured Clinical Interview for Axis I Disorders (SCID-I), and sociodemographic data of the participants were recorded. Patients scoring 10 points or more on the Yale–Brown Obsessive-Compulsive Scale were enrolled in the study. Results: The NO levels of patients with OCD were increased compared to the control group, but the increase was not statistically significant (P > 0.05). However, patients with OCD had significantly lower levels of ADMA, SDMA, and L-arginine compared with the controls (P < 0.001). Conclusion: We found a significant decrease in ADMA, SDMA, and L-arginine as NO inhibitors between the groups, possibly because of an increase in NO. However, the insignificant increase in NO suggests that ADMA, SDMA, and L-arginine play direct and potentially important roles in OCD biology.en_US
dc.identifier.doi10.3906/sag-1503-100en_US
dc.identifier.endpage782en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue3en_US
dc.identifier.pmid27513255en_US
dc.identifier.scopus2-s2.0-84964034600en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage775en_US
dc.identifier.trdizinid248558en_US
dc.identifier.urihttps://hdl.handle.net/11363/5734
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/248558
dc.identifier.urihttps://doi.org/
dc.identifier.volume46en_US
dc.identifier.wosWOS:000374327500028en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorBilici, Mustafa
dc.language.isoenen_US
dc.publisherTÜBİTAKen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectObsessive-compulsive disorderen_US
dc.subjectNitric oxideen_US
dc.subjectAsymmetric dimethyl arginineen_US
dc.subjectSymmetric dimethyl arginineen_US
dc.subjectL-arginineen_US
dc.titleLevels of nitric oxide, asymmetric dimethyl arginine, symmetric dimethyl arginine, and L-arginine in patients with obsessive-compulsive disorderen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
document (26).pdf
Boyut:
145.96 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale / Article
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ N/A ]
İsim:
license.txt
Boyut:
1.56 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Diğer Atıf Dizinlerdeki Yayınlar
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu