Total Gastrointestinal Flora Transplantation in the Treatment of Leaky Gut Syndrome and Flora Loss

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dc.contributor.authorKanlioz, Murat
dc.contributor.authorEkici, Ugur
dc.contributor.authorFerhatoglu, Murat Ferhat
dc.date.accessioned2024-09-11T19:53:29Z
dc.date.available2024-09-11T19:53:29Z
dc.date.issued2022
dc.departmentİstanbul Gelişim Üniversitesien_US
dc.description.abstractIntroduction The aim of this work was to treat patients with leaky gut syndrome (LGS) and gastrointestinal flora loss in a simple, inexpensive, permanent and effective way without the need for further treatment. Methods A total gastrointestinal flora transplantation (TGFT) procedure is performed by simultaneously transferring the flora taken from approximately 30 different anatomical sites, from the mouth to the anus, of healthy donors to the corresponding anatomical site of the patient using the endoscopic lavage method. Results Of the patients, 25 (44.6%) were female and 31 (55.4%) were male, totaling 56 (100%). The mean age was 32.88 +/- 15.78 years. Among the 56 patients enrolled in the study, TGFT had no efficacy in one patient, five patients underwent repeat TGFT during a mean follow-up period of 23.73 +/- 16.74 months, and the treatment was permanent in 50 patients; our success rate during the follow-up period was 89.3%. Conclusion In LGS, TGFT should be the gold standard treatment.en_US
dc.identifier.doi10.7759/cureus.31071
dc.identifier.issn2168-8184
dc.identifier.issue11en_US
dc.identifier.pmid36475195en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.7759/cureus.31071
dc.identifier.urihttps://hdl.handle.net/11363/8144
dc.identifier.volume14en_US
dc.identifier.wosWOS:000978544200033en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringernatureen_US
dc.relation.ispartofCureus Journal of Medical Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240903_Gen_US
dc.subjectceliac diseaseen_US
dc.subjectfecal microbiota transplantation (fmt)en_US
dc.subjectintestinal flora disorderen_US
dc.subjectfood allergy quality of lifeen_US
dc.subjecttotal gastrointestinal flora transplantationen_US
dc.subjectleaky gut syndromeen_US
dc.titleTotal Gastrointestinal Flora Transplantation in the Treatment of Leaky Gut Syndrome and Flora Lossen_US
dc.typeArticleen_US

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