Adenovirus-5 and adenovirus-37 seropositivity in obese patients

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dc.authoridhttps://orcid.org/0000-0002-0449-5915
dc.contributor.authorBostan, Nur Gamze
dc.contributor.authorAltınok, Özge
dc.contributor.authorBüyükaşık, Süleyman
dc.contributor.authorAlış, Halil
dc.contributor.authorÖner, Yaşar Ali
dc.date.accessioned2025-06-03T09:51:08Z
dc.date.available2025-06-03T09:51:08Z
dc.date.issued2024
dc.departmentSağlık Hizmetleri Meslek Yüksekokulu
dc.description.abstractBackground and Objectives: Obesity is a major health issue linked to conditions like diabetes, hypertension, and hyperlipidemia. Infectobesity suggests that certain microorganisms may contribute to obesity. Human adenovirus serotypes, particularly Human adenovirus type-36 (HAdV-36), Human adenovirus type-5 (HAdV-5), and Human adenovirus type-37 (HAdV-37), are thought to influence body fat regulation. This study investigatesthe relationship between Immunoglobulin G (IgG) positivity for HAdV-5 and HAdV-37 and obesity, aiming to provide data on the infectious etiology of obesity. Materials and Methods: Blood samples separated into serums from obese (BMI ≥30) and non-obese (BMI 18.5-25) individuals were tested for HAdV-5 and HAdV-37 seropositivity using ELISA kits and seropositivity rates between the groups were compared. Results: HAdV-37 antibody positivity was significantly higher in obese patients (39/48) compared to the control group (24/42) (p=0.011). For HAdV-5, antibody positivity was similar in both groups (26 individuals each) with no significant difference (p=0.461). No significant gender-related differences were found for either serotype. Conclusion: The study suggests HAdV-37 may be associated with obesity, while no such relationship was found for HAdV5. There was no gender association for either serotype. These results align with existing literature on HAdV-37, but further research is needed to confirm the link between adenoviruses and obesity and explore potential treatment options.
dc.identifier.endpage688
dc.identifier.issn2008-3289
dc.identifier.issn2008-4447
dc.identifier.issue5
dc.identifier.startpage684
dc.identifier.urihttps://hdl.handle.net/11363/9862
dc.identifier.volume16
dc.identifier.wos001354535400001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.institutionauthorBostan, Nur Gamze
dc.institutionauthoridhttps://orcid.org/0000-0002-0449-5915
dc.language.isoen
dc.publisherUNIV MEDICAL SCIENCES-DANISHGAH-I ULUM-I PIZISHKI-I TIHRAN, DEPT MICROBIOLOGY, SCH MEDICINE, POURSINA ST, KESHAVARZ BLVD, TEHRAN 00000, IRAN
dc.relation.ispartofIRANIAN JOURNAL OF MICROBIOLOGY
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectObesity
dc.subjectHuman adenovirus
dc.subjectSerotype
dc.subjectAdipocytes
dc.subjectInfections
dc.titleAdenovirus-5 and adenovirus-37 seropositivity in obese patients
dc.typeArticle

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