Osteoarthritis: Can it Be Reversed? A New Biological Treatment Technique for Treating Patients With Moderate to Advanced Gonarthrosis

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dc.contributor.authorKılıç, Bülent
dc.contributor.authorDemiroğlu, Murat
dc.contributor.authorÜnlü Özkan, Feyza
dc.contributor.authorSöylemez, Mehmet Salih
dc.contributor.authorTürkmen, İsmail
dc.contributor.authorSağlam, Yavuz
dc.contributor.authorÖzkan, Korhan
dc.date.accessioned2019-05-16T11:20:24Z
dc.date.available2019-05-16T11:20:24Z
dc.date.issued2017-01-02
dc.departmentSağlık Bilimleri Yüksekokuluen_US
dc.description.abstractOsteoarthritis of the knee is leading cause of disability in the elderly, all times. Although there are pharmacological and nonpharmacological treatment methods, these are generally insufficient to alleviate pain and the disability in advanced cases Although total knee arthroplasty improves quality of life and provides a generally high level of patient satisfaction for treatment of advanced gonarthrosis, it is not always without complications. Herein we present a new technique consisting of patellofemoral joint irrigation, simple osteophytectomy if needed, lateral patellar retinaculum release, subchondral drilling of the proximal tibia, percutaneous medial collateral ligament release, intra-articular injection of proximal tibial bone marrow, and the results of this treatment applied under local anesthesia in 20 knees of 13 patients. The mean VAS (Visual Analogue Scale) was 8.20 ± 0.68 prior to treatment and 3.33 ± 0.72 after treatment; the values were 18.67 ± 3.34 and 4.10 ± 3.15 for leg measurements, 7.80 ± 0.77 and 1.07 ± 0.96 for pain, 5.07 ± 2.28 and 1.80 ± 1.42 for walking, and 5.80 ± 0.92 and 1.23 ± 0.92 for daily living activities, respectively. All decreases were statistically significant (p = 0.001 for p < 0.01 in all cases). Biological treatment solutions to gonarthrosis without using foreign materials could decrease the need for prosthetic surgery and its related complications, as well as the need for further attempts at revision. In this study we presented a new biologic treatment for gonarthrosis. Keywords, Gonarthrosis, Subchondral drilling, Bone Marrow injection, Osteophytectomy.en_US
dc.identifier.doi10.19193/0393-6384_2017_2_050en_US
dc.identifier.endpage340en_US
dc.identifier.issn0393-6384
dc.identifier.issn2283-9720
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85015227572en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage335en_US
dc.identifier.urihttps://hdl.handle.net/11363/1258
dc.identifier.urihttps://doi.org/
dc.identifier.wosWOS:000397230700025en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherActa Medica Mediterraneaen_US
dc.relation.ispartofActa Medica Mediterraneaen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectResearch Subject Categories::MEDICINEen_US
dc.titleOsteoarthritis: Can it Be Reversed? A New Biological Treatment Technique for Treating Patients With Moderate to Advanced Gonarthrosisen_US
dc.typeArticleen_US

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