Sophora alopecuroides var. alopecuroides: Phytochemical composition, antioxidant and enzyme inhibitory activity of the methanolic extract of aerial parts, flowers, leaves, roots, and stems

Basit Öğe Kaydı
dc.authoridhttps://orcid.org/0000-0003-1980-1820en_US
dc.authoridhttps://orcid.org/0000-0001-5094-2520en_US
dc.contributor.authorArumugam, Radjassegarin
dc.contributor.authorSarıkürkcü, Cengiz
dc.contributor.authorMutlu, Muzaffer
dc.contributor.authorTepe, Bektaş
dc.date.accessioned2023-08-12T17:52:30Z
dc.date.available2023-08-12T17:52:30Z
dc.date.issued2021en_US
dc.departmentİstanbul Gelişim Meslek Yüksekokuluen_US
dc.description.abstractSophora alopecuroides L. are commonly used in traditional Chinese medicine for the treatment of various ailments such as refractory tinea, eczema, dermatitis, colpitis, bacillary dysentery, and other gastrointestinal diseases. The aim of this study was to investigate the chemical composition, antioxidant, and enzyme inhibitory activity of the aerial part, flower, leaf, root, and stems extracts of S. alopecuroides var. alopecuroides. Major compounds of the extracts were found to be ferulic acid, luteolin, hesperidin and pinoresinol. In many of the antioxidant activity assays, the root extract exhibited high activity. In CUPRAC reducing, phosphomolybdenum, ABTS, and DPPH tests, the activity of the root extract was 1.42, 2.45, 1.25, and 8.41 mg/mL, respectively. Root extract also exhibited significant activity in enzyme inhibitory assays. Tyrosinase, a-amylase, a-glucosidase, and acetyl cholinesterase (AChE) inhibitory activities of the extract were determined as 1.22, 2.97, 1.03, and 0.97 mg/mL, respectively. Chromatographic analysis showed that the root extract contained 462.25 mg/g pinoresinol and 256.23 mg/g vanillic acid as the major compounds. Pearson correlation analysis showed that besides flavonoids/phenolics, these phytochemicals also contributed to the activity of root extract. Therefore, it was concluded that these phytochemicals may be responsible for the activity of the root extract. The root extract of S. alopecuroides var. alopecuroides was thought to be an effective antioxidant and enzyme inhibitory agent.en_US
dc.identifier.doi10.1016/j.sajb.2020.10.009en_US
dc.identifier.endpage290en_US
dc.identifier.issn0254-6299
dc.identifier.issn1727-9321
dc.identifier.scopus2-s2.0-85094819725en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage282en_US
dc.identifier.urihttps://hdl.handle.net/11363/5297
dc.identifier.urihttps://doi.org/
dc.identifier.volume143en_US
dc.identifier.wosWOS:000767313800002en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorMutlu, Muzaffer
dc.language.isoenen_US
dc.publisherELSEVIER, RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDSen_US
dc.relation.ispartofSouth African Journal of Botanyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectSophora alopecuroides var. alopecuroidesen_US
dc.subjectBiological activityen_US
dc.subjectChemical compositionen_US
dc.titleSophora alopecuroides var. alopecuroides: Phytochemical composition, antioxidant and enzyme inhibitory activity of the methanolic extract of aerial parts, flowers, leaves, roots, and stemsen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
1-s2.0-S0254629920311200-main.pdf
Boyut:
1.27 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale / Article
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ N/A ]
İsim:
license.txt
Boyut:
1.56 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Web of Science ve Scopus Atıf Dizinlerindeki Yayınlar
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu