P-057 Development of a new sperm freezing medium containing serotonin to enhance sperm motility and viability

Abstract

Study question Is it possible to develop a new sperm freezing medium that improves sperm parameters after the freezing process in assisted reproductive techniques? Summary answer A new sperm freezing medium supplemented with Serotonin, L-Carnitine, and Coenzyme Q10 enhances sperm quality and improves sperm motility. What is known already Infertility affects 15% of couples worldwide, with 50% of infertility cases attributed solely to male factors. Reduced semen motility has been identified as a primary factor directly associated with infertility. The use of supplementation to enhance sperm quality has gained increasing popularity globally. The sperm freezing process in Assisted Reproductive Technology (ART) is critical for successful fertilization and can be performed in cases of severe oligozoospermia, as well as in conditions with potential future sperm count decline, such as spinal cord injury and multiple sclerosis. Sperm freezing media play a crucial role in enhancing the efficiency of the process.