The effect of aerobic exercise on immune biomarkers and symptoms severity and progression in patients with COVID-19: A randomized control trial

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dc.authoridhttps://orcid.org/0000-0001-5092-3549en_US
dc.authoridhttps://orcid.org/0000-0002-4936-373Xen_US
dc.contributor.authorMohamed, Ayman A.
dc.contributor.authorAlawna, Motaz
dc.date.accessioned2023-08-09T14:23:16Z
dc.date.available2023-08-09T14:23:16Z
dc.date.issued2021en_US
dc.departmentSağlık Bilimleri Fakültesien_US
dc.description.abstractBackground: The World Health Organization in March 2020 has announced that COVID-19 is a world pandemic because the number of infected cases increases rapidly. however, there are several available vaccines, their protection is limited to a certain period. Thus, the role of modalities that improve immune functions should be performed to counter COVID-19 viral load and decrease mortality rates. Objective: To investigate the effect of aerobic exercise on immune biomarkers, disease severity, and progression in patients with COVID-19. Design: A randomized controlled study. Participants: Thirty patients with COVID-19 participated in this study. Participants’ age ranged from 24 to 45 years old. Participants had a mild or moderate COVID-19. Participants were assigned randomly into two groups, exercise and control groups. There were two main dependent variables including blood immune markers and severity of respiratory symptoms. Interventions: All participants performed 2 weeks of moderate-intensity aerobic exercise for 40 min/ session, 3 sessions/week. The measurements were performed at baseline, and after 2-weeks. Results: At baseline measurements, there were non-significant differences between both groups in the Wisconsin scale total score, Leucocytes, Lymphocytes, Interleukin-6, Interleukin-10, Immunoglobulin-A, and TNF-a (P > .05). After the intervention, the Wisconsin scale (patient-oriented illness-specific qualityof-life) total score significantly decreased in the intervention group (P < .05); while, Leucocytes, Lymphocytes, and Immunoglobulin-A significantly increased in the intervention group (P < .05). Conclusion: The current study indicated that 2 weeks of moderate-intensity aerobic exercise decreased the severity and progression of COVID-19 associated disorders and quality of life. Also, a 2-weeks of aerobic exercise positively affected immune function by increasing the amounts of Leucocytes, Lymphocytes, Immunoglobulin A.en_US
dc.identifier.doi10.1016/j.jbmt.2021.07.012en_US
dc.identifier.endpage432en_US
dc.identifier.issn1360-8592
dc.identifier.issn1532-9283
dc.identifier.pmid34776174en_US
dc.identifier.scopus2-s2.0-85115144046en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage425en_US
dc.identifier.urihttps://hdl.handle.net/11363/5229
dc.identifier.urihttps://doi.org/
dc.identifier.volume28en_US
dc.identifier.wosWOS:000706408500030en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorMohamed, Ayman A.
dc.institutionauthorAlawna, Motaz
dc.language.isoenen_US
dc.publisherELSEVIER, RADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDSen_US
dc.relation.ispartofJournal of Bodywork and Movement Therapiesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectCOVID-19en_US
dc.subjectAerobic exerciseen_US
dc.subjectAerobic capacityen_US
dc.subjectImmune biomarkersen_US
dc.subjectImmune systemen_US
dc.titleThe effect of aerobic exercise on immune biomarkers and symptoms severity and progression in patients with COVID-19: A randomized control trialen_US
dc.typeArticleen_US

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