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    3D-printed polylactic acid (PLA)/polymethyl silsesquioxane (PMSQ)-based scaffolds coated with vitamin E microparticles for the application of wound healing
    (Springernature, 2024) Anjrini, Nasma; Karabulut, Hatice; Ulag, Songul; Ege, Hasan; Noberi, Cansu; Dogan, Ecem; Sahin, Ali
    Skin is part of the integumentary and excretory system, which helps protect the body against infections. The skin should be properly treated when it gets injured, which requires a long healing process. In this study, 15% (w/v) polylactic acid (PLA) and 1 and 2% (w/v) polymethylsilsesquioxane (PMSQ) scaffolds were fabricated using 3D printing technology, and the surfaces of each scaffold were coated with 5% ethylcellulose (EC)/vitamin E microparticles using the electrospray method. The morphologies of the scaffolds were characterized using a scanning electron microscope (SEM), and results showed that the pore sizes of the scaffolds ranged from 136 to 265 mu m. The vitamin E was completely released from the scaffolds within 5 h. MTT test was performed with fibroblast cells and results proved the biocompatibility of the scaffolds. These findings showed that the scaffolds may have good potential as a wound dressing material. The biodegradation test was performed in in vitro conditions and results showed that the surface coating with 5% EC/vitamin E microparticles on the 15% PLA/2% PMSQ scaffolds increased the degradation rate of the scaffolds.
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    Modeling of vibration for functionally graded beams
    (De Gruyter Open Ltd, 2016) Yigit, Gulsemay; Sahin, Ali; Bayram, Mustafa
    In this study, a vibration problem of Euler-Bernoulli beam manufactured with Functionally Graded Material (FGM), which is modelled by fourth-order partial differential equations with variable coefficients, is examined by using the Adomian Decomposition Method (ADM). The method is one of the useful and powerful methods which can be easily applied to linear and nonlinear initial and boundary value problems. As to functionally graded materials, they are composites mixed by two or more materials at a certain rate. This mixture at a certain rate is expressed with an exponential function in order to try to minimize singularities from transition between different surfaces of materials as much as possible. According to the structure of the ADM in terms of initial conditions of the problem, a Fourier series expansion method is used along with the ADM for the solution of simply supported functionally graded Euler-Bernoulli beams. Finally, by choosing an appropriate mixture rate for the material, the results are shown in figures and compared with those of a standard (homogeneous) Euler-Bernoulli beam.