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    Evaluation of chronic cough etiology, quality of life, and anxiety level in children
    (TURKISH ASSOC TUBERCULOSIS & THORAX, C/O AKIN KAYA MD, PROFESSOR, DEPT CHEST DISEASES, FAC MEDICINE, ANKARA 06100, TURKEY, 2022) Çatak, Arif İsmet; Güngör, Ali; Cinel, Güzin; Üneri, Özden Şükran; Göker, Zeynep; Toyran, Müge; Civelek, Ersoy; Dibek Mısırlıoğlu, Emine
    Introduction: To evaluate the quality of life and anxiety level of school-age children with chronic cough, and changes with treatment. Materials and Methods: Patients aged between 6-18 years with a chronic cough were included in this study. A control group was designed, and the scale scores were compared with each other. Results: The mean age of the 82 patients was 10.9 ± 3.8 years, 62 (75.6%) had at least one specific cough marker. Forty patients (48.8%) were diagnosed with asthma. At their first visit, the psychosocial health scores and the total scale scores (sum of physical and psychosocial total scores) were lower than the control group for both patients and parents. After the resolution of cough, their scores increased to the same level with the control group. It was also found that the level of anxiety was significantly higher than in the control group both before treatment and after the resolution period (p< 0.001 and =0.008, respectively). Conclusion: Asthma was the leading cause of chronic cough. Quality of life is impaired in children with chronic cough. Anxiety level in these patients increases and after symptoms improve, continues to be higher than that of healthy children.
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    Psychiatric symptoms in children with COVID-19, mothers’ psychological resilience and related factors: pandemic hospital inpatient experiences
    (TURKISH J PEDIATRICS, P K 66 SAMANPAZARI, 06240 ANKARA, TURKEY, 2022) Çöp, Esra; Akçay, Elif; Şenses Dinç, Gülser; Göker, Zeynep; Önal, Tuğçe; Gülhan, Belgin; Parlakay, Aslınur; Üneri, Özden Şükran
    Background. Information on psychological problems and affecting factors in children hospitalized with the suspicion or diagnosis of COVID-19 is limited. We aimed to screen the psychiatric symptoms of children hospitalized with COVID-19 in Ankara City Children’s Hospital and evaluate the caregivers’ depression, anxiety, stress, and resilience levels during hospitalization. Methods. Among the children and adolescents hospitalized in Ankara City Children’s Hospital between 1 May 2020 and 31 May 2020 due to the diagnosis of COVID-19, those who agreed to participate in the study were included. The Strengths and Difficulties Questionnaire (SDQ), the Depression Anxiety Stress Scale-21 (DASS21) scale, and the Brief Resilience Scale (BRS) were used to determine the symptoms. Results. The mean age of study group (n = 49) was 8.7 ± 5.0 years, 59.2% (n = 29) were girls. The mean children’s SDQ-externalizing problems scores were higher in the COVID-19 positive mothers group than the COVID-19 negative mothers’ group. The SDQ-total score was positively and strongly correlated with the DASS total score, DASS-depression score, and DASS-anxiety score. BRS scale scores were negatively correlated with the SDQtotal, externalizing, and DASS-21scale scores. Conclusions. COVID-19 positivity in mothers could be associated with externalizing problems in children. The high resilience of caregivers of inpatients seems to be related to less psychopathology in children. During hospitalization, caregivers’ psychological evaluation and psychosocial support may be important for preventive child mental health.
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    Serum Vitamin B12, Folate, and Ferritin levels in Children and Adolescents with Anxiety Disorders; Controlled Study
    (Van Tıp Dergisi, 2022) Uygun, Sabide Duygu; Göker, Zeynep; Karaca Kara, Fatma; Üneri, Özden Şükran
    Introduction: Vitamin B12, folate, and iron deficiencies both in early life and later can affect brain development and maintenance via potential mechanisms causing impaired synaptogenesis, myelination and neurotransmission, and increased neurotoxicity and oxidative stress, resulting in neuropsychiatric disorders like cognitive impairment, depression and anxiety. This study aimed to compare serum vitamin B12, folate, and ferritin levels between children and adolescents with anxiety disorders and healthy controls. Materials and Methods: The patient group consisted of 40 children aged 8-17 years who were newly diagnosed with anxiety disorders, had no physical or mental illness other than anxiety disorders, and whose serum vitamin B12, folate, and ferritin levels were measured in the last six months for any reason. As the control group, 40 subjects matched to the patient group for age and sex were selected from mentally and physically healthy children and adolescents. A semi-structured psychiatric interview was used for the diagnosis. Serum vitamin B12, folate, and ferritin levels were obtained from medical records. Results: Serum ferritin and folate levels in the patient group were found to be statistically significantly lower than the controls (34.0 ng/ml versus 46.9 ng/ml, 8.5±2.2 ng/mL versus 10.4±2.8 ng/mL, respectively), unlike serum vitamin B12 levels. Conclusion: Our initial findings may be scientifically important for further studies, which will show that low ferritin and folate levels are associated with childhood anxiety disorders. Whether there is a causal relationship between childhood-onset anxiety disorders and nutritional deficiencies should be investigated in longitudinal studies with larger samples.