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    The effects of skin closure by using mattress sutures or intracutaneous absorbable sutures after the Karydakis flap surgery because of sacrococcygeal pilonidal sinus. A comparative analysis
    (Edizioni Luigi Pozzi, 2019) Ekici, Ugur; Ferhatoglu, Murat Ferhat
    OBJECTIVE: After the pilonidal sinus surgery, the complications such as skin maceration, local wound dehiscence, wound site infection and recurrence may complicate the surgery. We aimed to compare the patients, who had undergone Karydakis flap surgery and the skin closure of whom was made by using intracutaneous or mattress sutures, with respect to wound site complications and recurrence. METHODS: The files of 230 Karydakis flap surgery patients were analyzed retrospectively. The patients were invited for re-examination and the lacking data were collected. The patients were divided into 2 groups in terms of skin closure methods as the mattress suture and the intracutaneous suture groups. In final control, the visual analogue scale (VAS) was used in order to determine their cosmetic satisfaction and it was investigated if any recurrence occurred. RESULTS: No statistically significant difference was observed in terms of skin closure time during surgery (p=0,143), duration of hospitalization (p=0.724), duration of surgery (p=0.3), postoperative wound site complications (p=0.152), time of return-to-work (p=0.498) and recurrence (p=0.89) between the groups. At the end of the follow-up period, no statistically significant difference was found between the groups in terms of patients' subjective assessments regarding the cosmetic appearance of wound site (p=0.981). CONCLUSIONS: Skin closures by using mattress suture or intracutaneous absorbable suture material after the Karydakis flap surgery are reliable methods that can be used, but intracutaneous closure method may reduce infection and maceration rates.
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    Total Gastrointestinal Flora Transplantation in the Treatment of Leaky Gut Syndrome and Flora Loss
    (Springernature, 2022) Kanlioz, Murat; Ekici, Ugur; Ferhatoglu, Murat Ferhat
    Introduction The aim of this work was to treat patients with leaky gut syndrome (LGS) and gastrointestinal flora loss in a simple, inexpensive, permanent and effective way without the need for further treatment. Methods A total gastrointestinal flora transplantation (TGFT) procedure is performed by simultaneously transferring the flora taken from approximately 30 different anatomical sites, from the mouth to the anus, of healthy donors to the corresponding anatomical site of the patient using the endoscopic lavage method. Results Of the patients, 25 (44.6%) were female and 31 (55.4%) were male, totaling 56 (100%). The mean age was 32.88 +/- 15.78 years. Among the 56 patients enrolled in the study, TGFT had no efficacy in one patient, five patients underwent repeat TGFT during a mean follow-up period of 23.73 +/- 16.74 months, and the treatment was permanent in 50 patients; our success rate during the follow-up period was 89.3%. Conclusion In LGS, TGFT should be the gold standard treatment.