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    A comparison of crystal phenol treatment, midline primary closure and Limberg flap reconstruction methods in female patients with primary pilonidal sinus disease
    (Edizioni Luigi Pozzi, 2021) Kanlioz, Murat; Uyanikoglu, Hacer; Ekici, Ugur; Karatas, Turgay; Tatli, Faik
    Pilonidal sinus disease (PSD) is a chronic problem often occurs in healthy hirsute men, however, women may also be affected. A range of conservative techniques to surgical flaps have been used to treat this condition. Currently, midline primary closure (MPC) is considered the standard of therapy; however, no statistically significant difference has been noted between primary versus secondary (Karydakis flap or Limberg flap) closure. Recently, flap reconstruction methods have been applied and superiority of these methods have been shown. Treatment methods should be employed to the individual, taking into account recurrence and complication rates of the method, recovery time, patients' preference and surgeon's skill.
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    The effects of skin closure by using mattress sutures or intracutaneous absorbable sutures after the Karydakis flap surgery because of sacrococcygeal pilonidal sinus. A comparative analysis
    (Edizioni Luigi Pozzi, 2019) Ekici, Ugur; Ferhatoglu, Murat Ferhat
    OBJECTIVE: After the pilonidal sinus surgery, the complications such as skin maceration, local wound dehiscence, wound site infection and recurrence may complicate the surgery. We aimed to compare the patients, who had undergone Karydakis flap surgery and the skin closure of whom was made by using intracutaneous or mattress sutures, with respect to wound site complications and recurrence. METHODS: The files of 230 Karydakis flap surgery patients were analyzed retrospectively. The patients were invited for re-examination and the lacking data were collected. The patients were divided into 2 groups in terms of skin closure methods as the mattress suture and the intracutaneous suture groups. In final control, the visual analogue scale (VAS) was used in order to determine their cosmetic satisfaction and it was investigated if any recurrence occurred. RESULTS: No statistically significant difference was observed in terms of skin closure time during surgery (p=0,143), duration of hospitalization (p=0.724), duration of surgery (p=0.3), postoperative wound site complications (p=0.152), time of return-to-work (p=0.498) and recurrence (p=0.89) between the groups. At the end of the follow-up period, no statistically significant difference was found between the groups in terms of patients' subjective assessments regarding the cosmetic appearance of wound site (p=0.981). CONCLUSIONS: Skin closures by using mattress suture or intracutaneous absorbable suture material after the Karydakis flap surgery are reliable methods that can be used, but intracutaneous closure method may reduce infection and maceration rates.
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    Efficacy of Intragastric Balloon Placement and Botulinum Toxin Injection in Bariatric Endoscopy
    (Lippincott Williams & Wilkins, 2020) Kanlioz, Murat; Ekici, Ugur; Tatli, Faik; Karatas, Turgay
    Background: To evaluate the results obtained from the combination of intragastric botulinum toxin A (IGBTA), intragastric balloon (IGB), and IGBTA(+)IGB in the treatment of obesity. Materials and Methods: Three separate treatment groups were set up. IGBTA, IGB, and IGBTA(+)IGB were administered to Group 1, 2, and 3, respectively. The body mass indexes (BMI) of patients were measured before and 6 months after the treatment. The intragroup and intergroup treatment results have been evaluated. PResults: The mean BMI decreased by 1.6 kg/m(2) in 40 patients who received IGBTA in group 1 (P<0.001), 3.95 kg/m(2) in 42 patients who received IGB in group 2 (P<0.001), and 4.9 kg/m(2) in 39 patients who received IGBTA and IGB in group 3 (P<0.001) after 6 months of treatment. The intolerance because of the application was the highest in group 3, followed by group 2. Conclusion: The treatment was most successful in group 3 followed by group 2 and group 1, respectively. The authors recommend the group 3 treatment, provided that nausea, vomiting, and flatulence have a high index of probability in such a treatment. However, when deciding between group 1 and group 2 treatments, the authors recommend opting for group 2 treatment that shows to be more efficient.
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    Reliability and Educational Features of YouTube Videos About Hernia Operations Performed Using Laparoscopic TEP Method
    (Lippincott Williams & Wilkins, 2020) Kanlioz, Murat; Ekici, Ugur
    Purpose: The purpose of this study was to assess the reliability, educational features, and popularity of YouTube videos on inguinal hernia operations using the laparoscopic total extraperitoneal (TEP) method on the basis of objective scoring criteria. Materials and Methods: We reviewed the first 50 videos on TEP. To assess the reliability and educational features of the videos, we used the DISCERN questionnaire score (DISCERN), Journal of the American Medical Association Benchmark criteria (JAMAS), and Global Quality Scores (GQS). We then used Video Power Index (VPI) to assess the videos' power on YouTube, and total extraperitoneal scoring (TEPS) to assess their conformity with the medical technique and also the accuracy, quantity, and quality of the information contained therein. Results: In the analysis of the source and contents of videos, the VPI, DISCERN, JAMAS, GQS, and TEPS values of all videos were found to be low. A positive correlation-at a level of 0.988-was found to exist between their number of views and VPI values (r: 0.988, P<0.001). Furthermore, we also observed a positive correlation-at a level of 0.811-between the video's likes and DISCERN scores (r: 0.811, P: 0.004). There was no other statistically significant relationship between other scores and the quantitative features of videos. A positive correlation-at a level of 0.709-was found between the videos' GQS and TEPS (r: 0.709, P: 0.022). No correlation was found among other scores. Conclusion: Depending on the scoring criteria, the lower scores obtained by those videos show that they do not provide a sufficient level of reliability and quality information.
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    Total Gastrointestinal Flora Transplantation in the Treatment of Leaky Gut Syndrome and Flora Loss
    (Springernature, 2022) Kanlioz, Murat; Ekici, Ugur; Ferhatoglu, Murat Ferhat
    Introduction The aim of this work was to treat patients with leaky gut syndrome (LGS) and gastrointestinal flora loss in a simple, inexpensive, permanent and effective way without the need for further treatment. Methods A total gastrointestinal flora transplantation (TGFT) procedure is performed by simultaneously transferring the flora taken from approximately 30 different anatomical sites, from the mouth to the anus, of healthy donors to the corresponding anatomical site of the patient using the endoscopic lavage method. Results Of the patients, 25 (44.6%) were female and 31 (55.4%) were male, totaling 56 (100%). The mean age was 32.88 +/- 15.78 years. Among the 56 patients enrolled in the study, TGFT had no efficacy in one patient, five patients underwent repeat TGFT during a mean follow-up period of 23.73 +/- 16.74 months, and the treatment was permanent in 50 patients; our success rate during the follow-up period was 89.3%. Conclusion In LGS, TGFT should be the gold standard treatment.