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    Evaluation of chronic cough etiology, quality of life, and anxiety level in children
    (TURKISH ASSOC TUBERCULOSIS & THORAX, C/O AKIN KAYA MD, PROFESSOR, DEPT CHEST DISEASES, FAC MEDICINE, ANKARA 06100, TURKEY, 2022) Çatak, Arif İsmet; Güngör, Ali; Cinel, Güzin; Üneri, Özden Şükran; Göker, Zeynep; Toyran, Müge; Civelek, Ersoy; Dibek Mısırlıoğlu, Emine
    Introduction: To evaluate the quality of life and anxiety level of school-age children with chronic cough, and changes with treatment. Materials and Methods: Patients aged between 6-18 years with a chronic cough were included in this study. A control group was designed, and the scale scores were compared with each other. Results: The mean age of the 82 patients was 10.9 ± 3.8 years, 62 (75.6%) had at least one specific cough marker. Forty patients (48.8%) were diagnosed with asthma. At their first visit, the psychosocial health scores and the total scale scores (sum of physical and psychosocial total scores) were lower than the control group for both patients and parents. After the resolution of cough, their scores increased to the same level with the control group. It was also found that the level of anxiety was significantly higher than in the control group both before treatment and after the resolution period (p< 0.001 and =0.008, respectively). Conclusion: Asthma was the leading cause of chronic cough. Quality of life is impaired in children with chronic cough. Anxiety level in these patients increases and after symptoms improve, continues to be higher than that of healthy children.
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    Psychological Distress and Drug Provocation Test-Related Anxiety Levels of Pediatric Patients and Their Parents
    (MARY ANN LIEBERT, INC, 140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801, 2022) Yılmaz Topal, Özge; Turgay Yağmur, İrem; Külhaş Çelik, İlknur; Üneri, Özden Şükran; Toyran, Müge; Karaatmaca, Betül; Civelek, Ersoy; Dibek Mısırlıoğlu, Emine
    Background: Drug provocation tests (DPTs) are the gold standard for the diagnosis of drug hypersensitivity reaction (DHR). To the best of our knowledge, there is no previous study reporting DPT-related anxiety levels in children and their parents. This study aimed to determine the difference in pre- and post-DPT anxiety levels of parents and children who were informed of the possibility of another DHR during the DPT, and to evaluate the relationship between parental psychological distress and anxiety levels. Methods: The study included children who underwent DPT in our clinic between July 1, 2019, and February 29, 2020, and accompanying parents who consented to participate. Age-appropriate State-Trait Anxiety Inventory scales were used to assess levels of state and trait anxiety in the patients and parents. The Symptom Checklist90-Revised (SCL-90-R) was used to screen for psychological symptoms in parents. Results: Data were collected from the parents of 69 children who underwent DPTs. The patients’ median age was 7.28 (interquartile range: 4.52–10.06) and their parents’ mean age was 35.28 – 5.38 years. Anxiety-related data were collected from 21 pediatric patients. The children and parents had higher state anxiety scores before DPT compared to after DPT. There was a positive correlation between the parents’ trait anxiety and pre-DPT state anxiety scores. In addition, parental pre-DPT state anxiety scores were positively correlated with SCL-90-R general severity index, somatization, anxiety, obsessive-compulsive, and depression subscale scores. Conclusion: The risk of allergic reaction in DPT may cause anxiety. A high level of parental anxiety before DPT, which gradually decreased after negative test results, was associated with history of drug-induced anaphylaxis in their children and high trait anxiety. Appropriate evaluation of patients and parents before DPT and providing detailed information may be important to reduce this anxiety.