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    An Altmetric Analysis of Top 100 Cited Articles on Perinatal Infection
    (BEZMIALEM VAKIF UNIV, ADNAN MENDERES BOULEVARD 34093 FATIH, ISTANBUL 00000, TURKEY, 2023) Borcak, Deniz; Bulut, Hatice
    Objective: Pregnant women and their fetuses are at increased risk of complications of viral, bacterial, and parasitic infections. For most infections, effective preventive strategies are available. Scientific studies on perinatal infections show advances in this field. The primary objective of this study was to evaluate the social attention paid to highly cited articles on perinatal infection in the last decade. Factors of altmetrics performance, including twitter mentions and the correlation between altmetrics and traditional citation counts were analyzed. Methods: We created the 100 top-cited articles (T100) list from the Web of Science database and altmetric.com website among 4,240 perinatal infection articles. Results: The most cited article “Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia” by Zhu H. published in the Translational Pediatrics Journal. The T100 list included 75 original scientific research publications and 25 review articles. On Twitter, 80 of the T100 articles were shared. Of the ten most tweeted articles, five were about 2019-nCoV, four were about Hepatitis B virus, and one was about Zikavirus. The number of AAS, average citations, and the number of tweets (NT) increased statistically significantly as the years increased. A statistically significant and strong correlation was found between AAS and the number of tweets. Conclusion: This study reflects the most influential publications to identify the trends of current studies and provides some directions for future studies to help researchers. Also, it presents a view on the subject of the level of interest shown by the scientific world on social media platforms to the most cited articles on the subject of perinatal infection.
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    Evaluation of cycloplegic and noncycloplegic performance of spot vision screener in detection of amblyopia risk factors using 2021 AAPOS guidelines
    (Elsevier, 2024) Bulut, Erkan; Dayi, Ozlem; Celik, Yusuf; Bulut, Hatice; Basar, Emel
    Purpose: This research evaluates the effectiveness of the Spot Vision Screener (SVS) before and after cycloplegia to detect amblyogenic refractive errors in children. Methods: Children ages 3 to 10 years old were screened by the SVS before and after cycloplegia. Sensitivity, specificity, positive and negative predictive value, paired t -test, Bland -Altman plot and receiver operating characteristic area under the curve were evaluated by comparing the results of the SVS (v3.0.05) measurements with the results of the cycloplegic Topcon autorefractometer according to the 2021 guidelines of the American Association for Pediatric Ophthalmology and Strabismus. Results: Both eyes of 211 patients aged 3 to 10 years old were included. Regarding the amblyopia risk factors, the noncycloplegic SVS had 65.7 % sensitivity, 94.9 % specificity, 81.2 % positive predictive value and 89.3 % negative predictive value. The SVS's sensitivity increased from 65.7 % to 81.9 % with cycloplegia compared to noncycloplegic SVS results. The sensitivity detection of hyperopia was improved from 4.2 % to 100 % after cycloplegia. Areas under the receiver operator characteristic curve for noncycloplegic SVS and cycloplegic SVS were 0.506 (95 % CI, 0.395 to 0.646, p = 0737) and 0.905 (95 % CI, 0.915 to 0.971, p < 0.001) for hyperopia, respectively. Using the +1.64 D revised cutoff criteria for hyperopia increased sensitivity from 4.2 % to 78 %. Conclusion: Noncycloplegic SVS measurements showed relatively high specificity in detecting amblyopia risk factors. The fact that noncycloplegic measurements have a very low sensitivity for hyperopia is an important weakness of the SVS, especially because hyperopia is the most frequently encountered refractive error in very young children. It should be noted that amblyogenic hyperopia may be overlooked by an SVS without cycloplegia.
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    New Age Borders Obtained from Spot Photoscreener by Using Multivariate Cluster Analysis
    (Pera Yayıncılık Hizmetleri, 2022) Bulut, Erkan; Çelik, Yusuf; Dayi, Özlem; Bulut, Hatice
    Objective: The aim of this study is to analyze all the variables obtained from photoscreener using hierarchical cluster analysis to create more homogeneous age groups for more reliable and consistent measurement by photoscreener. Methods: The variables obtained from photoscreener examination of consecutive children who attended the ophthalmology department were evaluated. Medical records of the children were evaluated to ontain data including refractive parameters, deviation angle, pupil diameter variables and the calculated spherical equivalent, the cylindrical power vector J0, J45 values. These variables were analyzed by the multivariate cluster analysis. Results: Based on a dendrogram, 4 main clusters of similar quality variables were created. The calculated spherical equivalent decreased gradually from cluster I to IV, from 0.745 D to –0.235 D. The average pupil size in the Ist cluster was 5.06 mm, while in the IVth cluster, it was 6.38 mm. The proposed new age borders are distinct and statistically significant (P <.001). The ultimate proposed new age borders were found as 1-20, 21-64, 65-101, and 102-120 months, respectively. Conclusions: We proposed new age borders for the evaluation of refraction and pupil size of children which create new groups with a statistically different and homogeneous distribution. The proposed new age borders in this research would provide more reliable and consistent measurement results for clinical diagnosis.
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    Obez ve Sağlıklı Çocuklarda Koroid Kalınlığının Klinik İlişkisi: Makine Öğrenimi Çalışması
    (Erkan Mor, 2023) Bulut, Erkan; Köprübaşı, Sümeyra; Dayi, Özlem; Bulut, Hatice
    Amaç: “Random forest” (RF), “support vector machine” (SVM) ve “multilayer perceptrons” (MLP) algoritmalarının performansını karşılaştırarak maküler koroid kalınlığı (MKT) ve peripapiller koroid kalınlığının (PPKT) obez ve sağlıklı çocukların sınıflandırılması üzerindeki etkisini analiz etmek. Gereç ve Yöntem: Bu prospektif karşılaştırmalı çalışmada yaşları 6-15 arasında olan 59 obez çocuk ve 35 sağlıklı çocuk optik koherens tomografi kullanılarak incelendi. MKT ve PPKT, fovea ve optik diskten 500 µm, 1.000 µm ve 1.500 µm mesafelerde ölçüldü. Çıkarılan tüm özelliklerin en belirgin olanlarını belirlemek için üç farklı özellik seçim algoritması kullanıldı. Çıkarılan özelliklerin sınıflandırma etkinliği, RF, SVM ve MLP algoritmaları kullanılarak analiz edildi ve bunların obezleri sağlıklı çocuklardan ayırt etmedeki etkinlikleri gösterildi. Ölçümlerin kesinliği ve güvenilirliği kappa analizi kullanılarak değerlendirildi. Bulgular: Korelasyon özellik seçimi algoritması, farklı özellik seçim yöntemleri arasında en başarılı sınıflandırma sonuçlarını üretmiştir. Obez ve sağlıklı grupları birbirinden ayırmada en belirgin özellikler PPKT temporal 500 µm, PPKT temporal 1.500 µm, PPKT nazal 1.500 µm, PPKT inferior 1.500 µm ve subfoveal MKT idi. RF, SVM ve MLP algoritmaları için sınıflandırma oranları sırasıyla %98,6, %96,8 ve %89 idi. Sonuç: Obezite, özellikle subfoveal bölgede ve optik disk başından 1.500 µm uzaklıktaki dış yarım dairede olmak üzere çocukların koroidal kalınlıkları üzerinde etkilidir. Hem RF hem de SVM algoritmaları, obez ve sağlıklı çocukları sınıflandırmada etkili ve doğru yöntemlerdir.
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    Ocular Biometry Characteristics and its Relationship with Age, Gender, Spherical Equivalent in Turkish Children
    (WOLTERS KLUWER MEDKNOW PUBLICATIONS, WOLTERS KLUWER INDIA PVT LTD, A-202, 2ND FLR, QUBE, C T S NO 1498A-2 VILLAGE MAROL, ANDHERI EAST, MUMBAI, Maharashtra 400059, INDIA, 2022) Dayi, Özlem; Bulut, Erkan; Karadağ, Mevlüde; Bulut, Hatice
    Background: Studying ocular biometric parameters in different populations and determining the relationship with personal characteristics can provide valuable information about ocular growth and help provide a better understanding of refractive errors. Aims: To describe distributions of ocular biometry and to evaluate its associations with age, gender, spheric equivalent in Turkish children. Patients and Methods: In this prospective study 344 children aged 3-14 years were evaluated. Parameters studied included axial length (AL), anterior chamber depth (ACD), and mean corneal radius (CR) measured with optical biometry. Cycloplegic refraction values were obtained using autorefractometer. The change of biometric parameters according to age and gender were evaluated. The relationship between ocular biometry parameters with refraction and age was analyzed by linear regression. Results: Mean spherical equivalent (SE), AL, ACD and AL/CR observed to be lowest in the preschooler group (P < 0.001). SE reduced with age, and a weak correlation observed between SE and age (r = ?0.333). AL and ACD had moderate and weak positive correlations with age respectively (r = 0.511; r = 0.304). There were negative correlations between SE with AL, ACD and AL/CR (r = -0.826; r = -0.540; r = -0.886). The strongest correlation with SE among these parameters was identified for AL/CR. AL and ACD were higher in boys, while the CR was lower in girls (p < 0.001). Conclusion: While AL in children in late schooler group is higher than European countries, it shows similar characteristics in early schooler group. In addition AL is lower in all age groups than Asian population sexcept preschooler group. With age AL increases, SE decreases and AL plays a key role in refractive development.

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