İstanbul Gelişim Üniversitesi Kurumsal Açık Erişim Arşivi
DSpace@Gelişim, İstanbul Gelişim Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Optimizing Multi-Channel Green Supply Chain Dynamics with Renewable Energy Integration and Emissions Reduction
(MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2024) Safaei, Mehdi; Al Dawsari, Saleh; Yahya, Khalid
In response to the global imperative of mitigating greenhouse gas emissions (GHGs) and
the shifting landscape of business models toward multi-channel structures, this study delves into
the intricacies of a green supply chain. Operating through both online and traditional channels with
uncertain demands, the producer’s distribution strategy prompts an exploration of supply chain
dynamics. Utilizing an integer programming model, this study calculates optimal prices, optimizes
total profit, and minimizes transportation costs to curtail carbon dioxide emissions, depending
on the transportation mode. Additionally, this study incorporates renewable energy sources into
the production and transportation processes to further minimize carbon dioxide emissions. The
integration of renewable energy not only supports environmental goals, but also contributes to the
overall profitability of the supply chain by reducing energy costs. Employing a theoretical technique
for linearization, the model, resolved through the Jimenez and TH methods, demonstrates efficacy in
reconciling economic and environmental goals. The Jimenez method enables the transformation of
fuzzy parameters into deterministic equivalents, allowing for a more reliable optimization during
uncertainty, while the TH method provides an interactive fuzzy multi-objective approach, aligning
the model’s dual objectives for both economic and environmental goals. Notably, when transportation
costs to both markets are equal, the model prioritizes devices with a lower environmental impact,
showcasing adaptability. Furthermore, the proposed solution empowers decision makers to influence
pricing and enhance the entire supply chain’s profitability. In conclusion, this research offers nuanced
insights, strategically aligning economic viability with environmental sustainability in the discourse
on green supply chains.
Trans-Achilles percutaneous fixation technique for posterior malleolus fracture: a cadaveric study
(BMC, CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND, 2024) Yağar, Hilal; Çiçek, Fatih; Ceranoğlu, Faruk Gazi; Karadağ, Hüseyin; Çınaroğlu, Selim
Background It has been reported that 43.6% of ankle fractures are accompanied by posterior malleolus fractures.
The aim of this study is to define a safe zone for posterior malleolus fractures by determining the locations of the
important anatomical structures in this region. Additionally, it aims to identify the trans-Achilles passage line for
Kirschner wire insertion through a posteroanterior approach for posterior malleolus fragments.
Methods Six below-knee amputee fresh-frozen leg cadavers were used in this study. A trans-Achilles Kirschner wire
was applied to the cadavers in the posteroanterior direction under the guidance of fluoroscopy. The areas where the
Kirschner wire passed were dissected, and their proximity to vital anatomical structures was measured.
Results In all cadavers, the transverse thickness of the Achilles tendon at the level of the trans-Achilles Kirschner
wire was 15.5 mm and the trans-Achilles Kirschner wire application was 18.6 mm from the sural nerve, 16 mm from
the posterior tibial tendon, and 12.16 mm from the flexor digitorum longus muscle. It was performed 15.16 and
14.6 mm from the posterior tibial artery and vein, 12.3 mm from the tibial nerve, 13.6 mm from the tibiofibular joint,
and 55.5 mm from the insertion site of the Achilles tendon to the calcaneus and at a sufficient distance from vital
anatomical structures.
Conclusions The proposed trans-Achilles percutaneous surgical technique is safe from neurovascular structures for
fixing posterior malleolar fractures. However, the long-term clinical outcomes of this technique need to be explored.
Level of evidence Level III, A cadaveric study.
Effect of a psychoeducation program based on cognitive-behavioral psychodrama techniques on premenstrual syndrome symptoms: a randomized controlled trial
(ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2-4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND, 2024) Sarıkaya, Nihan Altan; Meral, Deniz Kaya
Premenstrual syndrome is characterized by physical and psychological symptoms that negatively affect daily functioning. This study investigated the effect of a psychoeducation program based on cognitive-behavioral psychodrama techniques on premenstrual syndrome symptoms. This study utilized a 2 x 2 pretest-posttest, experimental-control group research design. The sample consisted of 32 participants randomized into experimental (n = 16) and control (n = 16) groups. The experimental group participated in a seven-session psychoeducation program based on cognitive-behavioral psychodrama techniques. Data were collected using a personal information questionnaire and the Premenstrual Syndrome Scale (PMSS). The experimental group demonstrated a significantly lower median posttest PMSS total and 'depressive affect', 'fatigue', 'irritability', 'depressive thoughts', 'changes in appetite' and 'changes in sleeping habits' subscale scores than the pretest score (p < .05). Moreover, the experimental group had a significantly lower median posttest 'anxiety' score than the control group (p = .021). A psychoeducational program based on cognitive-behavioral and psychodrama techniques can be used as an effective therapeutic intervention to relieve or managing premenstrual symptoms.
Transient analysis of functionally graded axisymmetric plates via finite element method in the Laplace domain
(TAYLOR & FRANCIS INC, 530 WALNUT STREET, STE 850, PHILADELPHIA, PA 19106, 2024) Doori, Silda Ghazi Mohammed; Noori, Ahmad Reshad
The principal goal of this research article is to examine the forced vibration of Functionally Graded Material (FGM) axisymmetric plates with the aid of the finite element method in the Laplace space. The material properties are assumed to be isotropic, linear viscoelastic, or elastic and vary continuously in the direction of the thickness of the plate. The governing equations of motion are transferred to the Laplace domain and solved for a set of Laplace parameters. Then, a modified Durbin’s inverse Laplace method is employed to retransfer the obtained results back to the time domain. A convergence analysis is conducted to optimize the number of Laplace parameters and time steps. An 8-node quadratic quadrilateral element featuring two degrees of freedom per node is employed to generate the model of the axisymmetric plates. Different loads such as step load, square wave, and sawtooth wave loads are used to observe the impact of load type on the transient response of FGM plates. In viscoelastic analysis, the Kelvin damping model is preferred, and the effect of the damping ratio is investigated. The obtained results are validated with the aid of the available literature and the accuracy of the suggested model is confirmed. It is carried out that the material variation significantly affects the dynamic behavior of the plates, for instance as the material coefficient increases, displacement amplitudes decrease, and periods increase. The novelty of this paper is the employment of the finite element method together with Laplace transformation for addressing the present class of problems for the first time.
New thiophene derivatives: chemoselective synthesis, antitumor effectiveness, structural characterization, DFT calculations, Hirshfeld surface, and Fukui function analysis
(BMC, CAMPUS, 4 CRINAN ST, LONDON N1 9XW, ENGLAND, 2024) Bin Muhsinah, Abdullatif; Alharbi, Mohammed M.; Kheder, Nabila Abdelshafy; Soliman, Saied M.; Ghabbour, Hazem A.; Mahmoud, Naglaa S.; Elhaty, Ismail A. M.; Mabkhot, Yahia N.
In this study, the chemoselective synthesis of two new thiophene derivatives is presented. The structure of newly
synthesized thiophenes derivatives; ethyl 4-acetyl-3-phenyl-5-(phenylamino)thiophene-2-carboxylate (5) and ethyl
(E)-4-(3-(dimethylamino)acryloyl)-3-phenyl-5-(phenylamino)thiophene-2-carboxylate (8) were established using
different FTIR and NMR spectral analyses. Compound 8 was isolated as single crystal and its 3D structure was
determined using X-ray crystallographic analysis. Possible intermolecular interactions that control the molecular
packing of 8 were elucidated using Hirshfeld topology analysis. The O…H (13.7%), H…H (55.3%) and C…C (2.3%)
intermolecular interactions are the most significant. Fukui functions showed that C4 in thiophene 5 and C3 in
thiophene 8 are the most reactive atoms for nucleophilic attack, while N9 in thiophene 5 and C1 in thiophene 8
are the most reactive atoms for electrophilic attack. Antitumor activity of thiophene 5 was assessed and the results
showed higher activity against HepG-2 (7.46 µg/mL) compared to the HCT 116 (12.60 µg/mL) cell line.
