Blink reflex in migraine headache
Özet
OBJECTIVE: Activation of trigeminovascular system is thought to play an important role in migraine pathogenesis. Blink reflex (BR) test is an easy method to study the trigeminal system. Latencies recorded in BR test were
evaluated to examine neurophysiological changes that occur in migraine patients.
METHODS: A total of 40 patients diagnosed with migraine (9 with aura and 31 without aura) according to the International Headache Society (IHS) International Classification of Headache Disorders, 2nd edition, and 30 healthy
control patients were assessed using BR test. Supraorbital nerve was stimulated on each side, and unilateral right
early component (R1), and bilateral late component (R2) latencies were evaluated.
RESULTS: Significantly longer latency values were recorded on both right and left sides (RR1 and LR1) as well
as both ipsilateral and contralateral R2 on the left side (LR2i and LR2c) in the migraine group compared to the
control group. Longer RR1 and LR1 latencies were found in migraneous patients who had an attack at the time
of study (p<0.01). There was no statistically significant correlation between the location of pain and latencies in
the interictal period (p>0.05). But significantly longer R1 and R2i latencies were found at the symptomatic side of
migraneous patients examined in the ictal period (p=0.037 and p=0.028 respectively). There was no statistically
significant correlation between the recorded latencies and gender, attack duration, attack frequency and migraine
type (p>0.05).
CONCLUSION: Results of BR test in the present study are thought to point to a dysfunction in brainstem and
trigeminovascular connections of patients with migraine headache and support the trigeminovascular theory of
migraine.
Cilt
3Sayı
1Bağlantı
https://hdl.handle.net/11363/5770Koleksiyonlar
Aşağıdaki lisans dosyası bu öğe ile ilişkilidir: