Anjrini, NasmaKarabulut, HaticeUlag, SongulEge, HasanNoberi, CansuDogan, EcemSahin, Ali2024-09-112024-09-1120242522-57312522-574Xhttps://doi.org/10.1007/s42247-024-00711-3https://hdl.handle.net/11363/7664Skin is part of the integumentary and excretory system, which helps protect the body against infections. The skin should be properly treated when it gets injured, which requires a long healing process. In this study, 15% (w/v) polylactic acid (PLA) and 1 and 2% (w/v) polymethylsilsesquioxane (PMSQ) scaffolds were fabricated using 3D printing technology, and the surfaces of each scaffold were coated with 5% ethylcellulose (EC)/vitamin E microparticles using the electrospray method. The morphologies of the scaffolds were characterized using a scanning electron microscope (SEM), and results showed that the pore sizes of the scaffolds ranged from 136 to 265 mu m. The vitamin E was completely released from the scaffolds within 5 h. MTT test was performed with fibroblast cells and results proved the biocompatibility of the scaffolds. These findings showed that the scaffolds may have good potential as a wound dressing material. The biodegradation test was performed in in vitro conditions and results showed that the surface coating with 5% EC/vitamin E microparticles on the 15% PLA/2% PMSQ scaffolds increased the degradation rate of the scaffolds.eninfo:eu-repo/semantics/closedAccessElectrosprayMicroparticlesPLAPMSQVitamin EWound healing3D printingArticle10.1007/s42247-024-00711-32-s2.0-85193079171WOS:001223831800002N/A