Bademler, SuleymanKoza, Kadir B.Ucuncu, Muhammed Z.Tokmak, HandanBakir, BarisOral, Ethem N.Asoglu, Oktar2024-09-112024-09-1120191530-45151534-4908https://doi.org/10.1097/SLE.0000000000000664https://hdl.handle.net/11363/7841This study was designed to evaluate the impact of a standardized laparoscopic total mesorectal excision (TME) on the long-term oncologic outcome. Unselected consecutive patients with rectal cancer underwent a standardized laparoscopic TME with medial to lateral approach encompassing 9 sequential steps. From 2005 to June 2012, laparoscopic sphincter-preserving TME was attempted in 217 patients. Mean follow-up of all patients was a median of 91 months (range, 3 to 164 mo). The local recurrence rate was 6.5%, and the distant recurrence rate was 19.8%. The 10-year disease-free survival (DFS) rates were 76.4% and overall survival (OS) was 67.1%. In the converted group, DFS and OS were 50% and 46.7%, respectively. In the laparoscopic group, DFS and OS were 78.3% and 68.5%, respectively. A standardized laparoscopic sphincter-preserving TME resulted in a favorable long-term oncologic outcome in unselected patients with rectal cancer. Conversion to open surgery has impaired OS and DFS.eninfo:eu-repo/semantics/closedAccessrectal cancerlaparoscopic sphincter-preserving surgerytotal mesorectal excisionArticle29535436110.1097/SLE.0000000000000664311078502-s2.0-85069201996WOS:000490743400014Q3