İstanbul Gelişim Üniversitesi Kurumsal Açık Erişim Arşivi
DSpace@Gelişim, İstanbul Gelişim Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Multi-Wave, Breather, and Interaction Solutions to Akbota Equation for The Heisenberg Ferromagnet-Type Model Arising in Nonlinear Physical Sciences
(Springer India, 2025) Kaya Sağlam, Fatma Nur; Kopçasız, Bahadır
This paper investigates the integrable Akbota equation, a Heisenberg ferromagnet-type
model. It is a basic tool for understanding curve and surface geometry. The interactions
between atoms’ magnetic moments are described by Heisenberg ferromagnetism. This equation is investigated utilizing the logarithmic transformation, the multi-wave technique, the
homoclinic breather approach, and the interactional solution using the double exp-functions
strategy. A well-known idea in nonlinear research, the multi-wave approach clarifies that three
waves interact under particular resonance circumstances. A breather wave is a localized oscillatory solution that preserves its form as time progresses. Additionally, we will analyze the
dynamics of the newly derived solutions through graphical representations, assigning suitable values to the parameters. The offered methods are clear and precise, making it possible
to extend the established form to additional nonlinear models. In contrast to prior investigations in the literature, our results are noteworthy. These results could be significant for further
exploration of such frameworks to address nonlinear issues in applied sciences. Furthermore,
the results enhance our understanding of fluid propagation and incompressible fluids. The
solutions derived for the Akbota equation are novel and have not been recorded in previous
research. Some of the solutions are shown using 3d, contour, density, and 2d representations
created with the Maple software. The accuracy of all solutions has been confirmed.
Novel 1,3-oxathiole derivatives: Efficient one-pot synthesis, antitumor efficiency, X-ray crystallographic, Hirshfeld surface, and Fukui function analysis
(Elsevier B. V., 2025) Muhsinah, Abdullatif Bin; Kheder, Nabila A.; Soliman, Saied M.; Ghabbour, Hazem A.; Elhaty, Ismail A. M.; Gad, Nehad H.; Mabkhot, Yahia N.
An efficient one-pot access of two novel 1,3-oxathiole derivatives namely, ethyl (Z)-2-(4-acetyl-5-methyl-1,3-
oxathiol-2-ylidene)-2-cyanoacetate; 7a and ethyl (Z)-2-(1-cyano-2-ethoxy-2-oxoethylidene)-5-methyl-1,3-oxathiole-4-carboxylate; 7b is described. The title compounds were prepared from the reaction of ethyl 2-cyanoacetate with carbon disulfide and 3-chloropentane-2,4‑dione or ethyl 2‑chloro-3-oxobutanoate in a K2CO3/DMF
mixture. Their chemical structures were fully identified and characterized using spectral (IR, NMR, MS) and Xray single-crystal structure analysis. The molecules of 7a and 7b are connected in the 3D via C–H…O and π-π
stacking interactions, respectively. Using Hirshfeld analysis, the H…H, O…H, and N…H contacts dominate the
molecular packing of 7a 28.3, 25.0, and 15.9 %, respectively, while 38.8, 20.3 and 15.0 % for 7b, respectively.
The local reactivity was determined using Fukui functions and dual descriptor indices. According to the Fukui
function, the susceptibility to nucleophilic attack was mainly detected on C2, C5, C6, and O7 in 7a, and C2, C5,
and O7 in 7b The in vitro cytotoxicity of the synthesized compounds was evaluated against cancer cell lines:
MCF-7 (breast cancer), HepG2 (liver cancer), and HCT116 (colorectal cancer). Compound 7a is particularly
effective against HepG2 cells with an IC50 value of 7.8 ± 0.7 μg/mL and impacts MCF-7 and HCT116 with IC50
values of 26.5 ± 1.8 and 26.3 ± 1.4 μg/mL, respectively. In contrast, compound 7b has moderate activity against
HepG2 but limited effect on the other two lines.
Investigation of protein level, amino acid profile and cytotoxic effects of plantbased proteins and meat analogues
(Gumushane University, 2025) Yılmazer, Yasemin; Tekiner, İsmail Hakkı; Çavdar, Aleyna; Durak, Şermin; Abdülhamitoğlu, Rula
According to the Nova food classification system, plant proteins containing vegan analogues are classified into processed
and ultra-processed. The recent sectoral developments highlight the importance of nutritional assessments of plant
proteins and vegan analogues. This study investigated the protein level, essential (EAA)- and non-essential (non-EAA)
amino acid profiles, and cytotoxic effects of plant-based proteins and meat analogues. Therefore, four meat products
(burger meatball, pastırma, stuffed meatball, and sausage), soy and pea proteins, and four meat analogues were purchased
from retail markets. All samples were subjected to the Kjeldahl test for protein content (%), LC-MS/MS test for EAAand non-EAA profiles, and MTS assay for their cytotoxic effects. The results showed that the protein contents of soy
protein, pea protein, meat analogues, and animal-origin meat products were determined to be 60.9%, 81.8%, 18.5 ± 9.3%,
and 18.1 ± 9.7%, respectively. The EAA to non-EAA ratio in the meat analogues and meat products was 29.2/70.8 and
27.9/72.1, respectively. Besides, the MTS test indicated that the cell viability of HCT-116 cells at 24th and 48th h in the
sausage analogues was significantly reduced by 59.84 ± 1.84%. In contrast, in pastırma and beef stuffed meatball
analogues at 48th h, it was significantly decreased by 57.34 ± 0.52% and 62.70 ± 0.79%, respectively (p<0.05). Overall,
we concluded that the health effects of processed and ultra-processed plant-based proteins and meat analogues on human
health need further investigation through bioavailability and molecular-based techniques.
Istanbul Gelisim University School of Foreign Languages: Monthly Bulletin (June 2025)
(İstanbul Gelişim Üniversitesi Yabancı Diller Yüksekokulu, 2025) İstanbul Gelişim Üniversitesi Yabancı Diller Yüksekokulu
Using English Outside the Classroom: Why It Matters
In an English Preparatory Program, classroom learning gives you a strong foundation—
but real progress happens when you start using English in daily life. One ofthe biggest
mistakes students make is limiting English to homework and exams. The truth is, language
grows when it’s lived, notjust studied.
Weekly Press Release of Istanbul Gelisim University (Issue 294) (2-13 June 2025)
(İstanbul Gelişim Üniversitesi / Istanbul Gelisim University, 2025) İstanbul Gelişim Üniversitesi Rektörlüğü
THIRD FACULTY OF APPLIED SCIENCES END OF TERM EXHIBITION HAS BEEN OPENED!
Istanbul Gelisim University (IGU) Faculty of Applied Sciences (UBF) brought
together student projects and academic productions with the Third Applied
Sciences Exhibition held within the scope of the 2024-2025 academic year. The
works developed by students from all departments within the faculty within the
scope of applied courses and projects attracted great attention in the exhibition
area in the Rectorate building.
https://gelisim.edu.tr/en/gelisim-news-third-faculty-of-applied-sciences-end-of-term-exhibition-has-been-opened
